为了给植物核苷二磷酸激酶NDPKs的进一步研究提供参考，总结了植物核苷二磷酸激酶(NDPKs)的分类、亚细胞定位、功能及其在植物基因工程中的应用。重点分析了NDPKs功能方面研究的最新进展，NDPKs不仅能够作为一种“看家酶”，维持细胞NDP和NTP代谢平衡，而且还是一组多功能蛋白，参与植物细胞的生长与分化、光敏色素A、紫外线-B、热击响应及氧化胁迫响应中的信号传导等多种生命活动过程，甚至具有核酸酶活性。最后指出植物NDPKs的研究方向，并展望了其在植物抗逆基因工程方面良好的应用前景。

This review summarizes the plant nucleoside diphosphate kinase (NDPKs, NDPK kinase EC 2.7.4.6) in terms of their classification, subcellular location, function and application in plant gene engineering. Research advances of NDPKs function is analyzed with emphasis. Not only NDPKs as a housekeeping enzyme can maintains the intracellular levels of all (d)NTPs used in biosynthesis except ATP, but also NDPKs are also one group of multifunctional protein. NDPKs participate in many vital cellular processes such as regulation of growth and development, signal transduction in response to phytochrome A, UV-B irradiation, heat shock and oxidative stress, and even has the activity as nuclease. Finally, this review points outs the research direction of plant NDPKs, and describes the application prospect in plant stress resistance genetic engineering, which will provides the reference for the further research.