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农学学报

农学学报 ›› 2017, Vol. 7 ›› Issue (4): 15-19.doi: 10.11923/j.issn.2095-4050.cjas16100003

• 植物保护 • 上一篇    下一篇

新杀螨活性化合物螺甲丁酯 (AC-118) 的合成及应用

鞠光秀,陈格新,许良忠   

  1. 青岛科技大学 化学与分子工程学院,青岛科技大学 化学与分子工程学院,青岛科技大学 化学与分子工程学院
  • 收稿日期:2016-10-08 修回日期:2016-12-16 接受日期:2016-12-23 出版日期:2017-04-26 发布日期:2017-04-26
  • 通讯作者: 许良忠 E-mail:jgx0718@163.com
  • 基金资助:
    无基金

Synthesis and Application of New Acaricidal Compound 3-(2,4,6-trimethyl-phenyl)-2-oxo-1-oxaspiro[4.4]non-3-en-4-yl butane-1-sulfonate

  • Received:2016-10-08 Revised:2016-12-16 Accepted:2016-12-23 Online:2017-04-26 Published:2017-04-26

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摘要： 现阶段杀螨剂的大量使用，导致害螨的抗药性逐年增加，因此有必要开发新型、高效的杀螨剂。参照螺甲螨酯的合成方法，合成了新杀螨活性化合物螺甲丁酯(AC-118)。分别测试了AC-118 对朱砂叶螨螨卵和雌成螨的毒力，并考察了其对山楂叶螨的田间防效。结果表明：AC-118 的结构经1H NMR确认。初步活性试验显示：其对朱砂叶螨螨卵和雌成螨的LC50分别为2.4 mg/L和6.7 mg/L；田间施药后14天，2000 倍和3000 倍剂量下，24?-118 SC对山楂叶螨的防效分别为96.1%和93.0%，24?-118 ME的防效分别为97.2%和94.6%；3000 倍剂量下，24%螺甲螨酯SC的防效为93.9%。AC-118 与螺甲螨酯的防效相当。相对于传统杀螨剂来说，AC-118 具有活性高、速效性好和持效期长的优点，可对其进行进一步的开发研究。

关键词: 菏麦20, 菏麦20, AMMI模型, 丰产性, 稳产性

Abstract: With the frequent and extensive use of acaricides, mites had developed increasing resistance to acaricides. It’s necessary to prepare new type of highly effective acaricide. A new acaricidal compound 3-(2,4,6-trimethyl-phenyl)-2-oxo-1-oxaspiro[4.4]non-3-en-4-yl butane-1-sulfonate (AC-118) was synthesized refer to the synthetic method of Spiromesifen. The toxicity of AC-118 against eggs and female adults of Tetranychus cinnabarinus were tested by leaf-dipping method and slide-dip method, respectively. The field control efficacy against Tetranychus vinnensis was also evaluated. The structure of AC-118 was confirmed by 1H NMR. The preliminary bioassay results showed that LC50 of AC-118 against eggs and female adults of Tetranychus cinnabarinus were 2.4 mg/L and 6.7 mg/L, respectively. 14 d after spraying in field, at the dosage of 2000 and 3000 times, 24% AC-118 SC provided 96.1% and 93.0% field control efficacy against Tetranychus cinnabarinus, respectively. 24% AC-118 ME provided 97.2% and 94.6% field control efficacy, respectively. At 3000 times, 24% Spiromesifen SC provided 93.9% field control efficacy. The control effect of AC-118 on Tetranychus cinnabarinus was equivalent to that of Spiromesifen. Compared with the traditional acaricides, AC-118 had the advantages of high bioactivity, rapid availability and long efficacy duration. Further development and research could be carried on to AC-118.