Abstract: The breeding methods and application status of potato were summarized in this paper. Breeding methods on potato were described including introduction identification, seed breeding, bud mutation breeding, cross-breeding, mutation breeding, molecular marker assistant breeding, cell engineering techniques breeding and transgenic engineering breeding. Then, the authors discussed the breeding situation and existing problems, and made an outlook on new ways that could be used in potato breeding, including exploring of potato germplasm resources, application of biotechnology in breeding, combination of conventional breeding and molecular breeding. The research could provide theoretical basis and technical support for potato breeding and lay the foundation for varieties cultivation.