Abstract: By spraying different doses of sorghum chlormequat and ethephon solution, field experiments were designed to ascertain the effect of chlormequat and ethephon solution on sorghum growth, yield and quality. The experiments were conducted with two factors in four levels in a randomized block design with three replications, spraying the regulators at the jointing stage (July 5, 2014). Ethephon and chlormequat, each had six concentration gradients. Ethylene dilutions were 100 times, 200 times, 400 times, 800 times, 1000 times and water control; cycocel dilutions were 100 times, 250 times, 400 times, 550 times, 700 times and water control. Results showed that the main role of two kinds of growth regulators was to inhibit the biosynthesis of gibberellin and control elongation growth of plants. The plant dwarfing effect of ethephon (heading stage) increased by 29.32%, 34.58%, 21.80%, 21.8%, 2.18% compared with the control; while that of ethephon (maturity stage) increased by 21.07%, 22.16%, 19.77%, 18.63%, 12.11% compared with the control. Dwarfing effect of chlormequat (heading stage) increased by 5.43%, 13.18%, 3.10%, 3.88%, 8.53% compared with the control; while that of chlormequat (maturity stage) increased by 9.94%, 29.19%, 13.64%, 18.01% , 14.91% compared with the control. Spraying different concentrations of ethephon, CCC on sorghum had a certain impact on grain quality. Spraying ethephon diluted 200 times had the most obvious improvement in grain quality, chlormequat diluted 250 times had significant effect. Dwarfing effect of ethephon spraying was more significant than that of chlormequat, but in improving sorghum photosynthetic parameters, chlorophyll content and the yield, the two regulators had no obvious difference. In the production, spraying ethephon and chlormequat at jointing stage can effectively control the sorghum plant height, yield achieve densification increase.