Abstract: The aims were to normalize the wheat-cotton relay intercropping planting, solve the contradiction of contending soil between food stuff and cotton, stabilize cotton production and achieve good quality and high yield as well as efficiency of grain and cotton. By summarizing years of experiences of the wheat-cotton relay intercropping cultivation, and screening published research results, the cultivation techniques were combined, optimized and verified through field tests. Based on the technology standardization requirements, wheat-cotton relay intercropping cultivating techniques were elaborated in varieties selection, sowing techniques, waterfertilizer management, plant pruning and topping, chemical control, disease as well as pest control etc, to solve the conflict of contending for water, fertilizer, shading light during symbiotic period. The double cropping cotton could open bolls early and intensively by making full use of time, space, light energy and land resources, which was beneficial to improve the quality and production of grain and cotton, and to achieve synchronized growth of grain and cotton. The regulation was made to provide convenience for farmers with field management operation, which was an effective way to solve the contradiction of contending soil between food stuff and cotton, to stabilize the cotton production, to achieve the double harvest of wheat and enhance the economic income of farmers.