Abstract: The study aimed to acquire the high efficiency fungicides to the pathogen of cineraria sclerotinia rot..The susceptibility of Sclerotinia sp. isolated from cineraria on ten fungicides was tested using the mycelium growth rate method. The results indicated that, the pathogen had high sensitivity to the traditional organic sulfur fungicides, among them the toxicity of thiram with the EC50 value was 0.8742 μg/mL to Sclerotinia sp. and EC90 value was 19.4750 μg/mL. While the inhibitory activity of mancozeb was lower than thiram. For the modern selective fungicides, the susceptibility of fungicides declined following the order of prochloraz, difenoconazole, procymidone, iprodione tebuconazole, myclobutanil, triadimefon and azoxystrobin. Among them, the triazole fungicides prochloraz had the highest activity to the pathogen and the EC50 value was 0.0418 μg/mL and EC90 value was 0.3138 μg/mL, respectively. Similarly, in the kind of two methylimide fungicides, the procymidone had the highest activity to the pathogen and the EC50 value was 0.2113 μg/mL and EC90 value 0.5889 μg/mL. While the inhibitory activity of azoxystrobin was the lowest with the EC50 was 7.6224 μg/mL and EC90 59.5022 μg/mL. Therefore, prochloraz and procymidone had higher toxicity to the pathogen of cineraria sclerotinia rot and could be recommended as the alternatives for the control of the disease. Furthermore, the reasonable blending of protective fungicides and selective fungicides was advocated for improving the control effect.