Abstract:

This review summarizes the plant nucleoside diphosphate kinase (NDPKs, NDPK kinase EC 2.7.4.6) in terms of their classification, subcellular location, function and application in plant gene engineering. Research advances of NDPKs function is analyzed with emphasis. Not only NDPKs as a housekeeping enzyme can maintains the intracellular levels of all (d)NTPs used in biosynthesis except ATP, but also NDPKs are also one group of multifunctional protein. NDPKs participate in many vital cellular processes such as regulation of growth and development, signal transduction in response to phytochrome A, UV-B irradiation, heat shock and oxidative stress, and even has the activity as nuclease. Finally, this review points outs the research direction of plant NDPKs, and describes the application prospect in plant stress resistance genetic engineering, which will provides the reference for the further research.