Abstract: Abstract: Comprehensively promoting the cultivation in practice innovation ability of animal medicine students is in line with the modern educational idea and the trend of our future development. To meet the rapid development of society and the needs of high-quality application-oriented talents of livestock industry in our country, as well as, to coordinate economic transformation and rapid development of Liaoning old industrial base, Shenyang Agricultural University, as the main agricultural college in Liaoning Province, explored practical innovation ability culture ways of undergraduate students of animal medicine with the aim of building a more scientific and rational training model. The main reform points were as follows. ① to Make full use of campus internal and external practice base, some business units were introduced into the practice of teaching using the “campus and off-campus” internship model. ② through practical activities and actively participating in the second class, we tried to enhancing the ability of undergraduate students in exploring of science, and through the merging of curricular and extracurricular education, we tried to strengthening the cultivation of students in practical innovation ability. ③ We tried to enhancing practical innovation ability culture of undergraduate students of animal medicine through strengthening thesis quality. ④ We performed the reform of teaching methods, and created an academic atmosphere with a variety of innovative personnel training methods. Through a series of reforms and the integration of practical innovative education and professional teaching, we promoted well the innovative awareness, practical skills, and social skill training of students.