Abstract: To search the high-efficiency, long time-efficiency and safe fungicides against Eucalyptus purple blotch, difenoconazole 10% WG, thiophanate-methyl SC at the concentration of 500 g/L and 50% carbendazim WP were evaluated through experiment in forest and clear water as CK. The results showed that: 3 kinds of fungicides all had relatively good effect for controlling eucalyptus purple blotch. The most of eucalyptus were able to restore growth, grow new shoots after the 3rd round of spray at the interval of 10 days. And, the 1500 times of difenoconazole 10% WG possessed comparatively satisfied effect on Eucalyptus purple blotch. After using the fungicide, its disease index was 25.24, and its controlling effect reached 40.24%; followed by the 600 times of thiophanate-methyl SC, its disease index was 27.09, and its controlling effect reached 35.87%; and the 500 times of 50% carbendazim WP, its disease index was 32.21, and its controlling effect was 23.74%; the disease index of CK was 42.24. The above fungicides were safe to Eucalyptus.