Abstract: The aim was to standardize the high-yield cultivation techniques regulation of ‘Lunxuan 22’, a new variety of wheat with high resistance to Fusarium head blight (FHB), to form a complete set of fine variety and good cultivation measures, to achieve high yield, good quality and contribute to ensure safety of foods as well as to reduce the pollution. By means of trial of its high yield cultivation technique and large area production demonstration, the breeding process of ‘Lunxuan 22’ was introduced, and its main characteristics, yield performance, quality, adaptation range and utilization prospect were analyzed. The high-yield cultivation techniques regulation of wheat variety ‘Lunxuan 22’ were summed up. The regulation set the yield components, seed treatment, fertilization and field management, etc. ‘Lunxuan 22’ has characteristics of outstanding traits, high yield, good quality, and has wide application prospect in the Huaihe River and the Yangtze River.