Abstract: In order to change the way of choosing compound fertilizer technique for winter wheat randomly and blindly, meanwhile solving the problem on low yield in winter wheat because of inadequate fertilization, the field trial, on the typical farmland, was researching the comparison on winter wheat by applying common S-based compound fertilizer, in different technique during 2010-2012.The treatments, designed including different compound fertilizer technique, mixed fertilizer and French AZF, were applying for base fertilizer 600kg/ha by proportion of N-P2O5-K2O=15-15-15. The result showed that the winter wheat yield of mixed fertilizer technique and French AZF technique were increased significantly,which had a significant difference between the 2 treatments, but economic benefit didn't have significant difference.The yield of mixed fertilizer technique and French AZF technique treatments were 3262.0kg/ha、3168.0kg/ha,increased by 65.7%、63.8% compared to CK, and the economic benefit increased 5278.20yuan、4252.80 yuan. The research suggested that the mixed fertilizer and French AZF technique should be chose for base fertilizer on winter wheat.