Abstract: The study aims to master the present resistance characteristics of Myzus persicae (Sulzer) populations to common insecticides and the resistance distribution of the medicament in Yunxi City. The author used the indoor bioassay methods, tested 6 kinds of common insecticides on 4 field populations and 1 nature reserve sensitive population, and obtained the resistant levels of the field populations. The results showed that Tonghai population had the highest sensitivity, which was from sensitive to extremely high levels (0.64-409.52 times); Yuanjiang population was from sensitive to extremely high levels (0.19-317.55 times); Chengjiang population was from sensitive to the high levels (0.59-77.71 times); Hongta District population had the lowest levels, which was from sensitive to sensitive falling levels (0.38-4.79 times). Resistance to 6 drugs was in an order as: pirimicarb (4.79- 409.52 times) > deltamethrin (4.27- 80.22 times) > chlorpyrifos (1.97- 13.95 times) > imidacloprid (0.93-5.74 times)> pymetrozine (1.25-3.49 times)> abamectin (0.19-0.64 times). Among the 4 populations in Yuxi, except the Hongta District population, the other three were all resistant to pirimicarb, deltamethrin and chlorpyrifos. In the prevention and control of vegetable Myzus persicae (Sulzer), chlorpyrifos, abamectin, pymetrozine and imidacloprid should be applied in turn with appropriate levels, and the use of pirimicarb and deltamethrin should be stopped.