Abstract: Sorghum variety‘Jinza 18’was used as material, the effect of different contents sodium selenite seed soaking on seed germination and seeding growth of sorghum were studied by the method of indoor germination test. At the same time, the effect of different contents sodium selenite seed soaking on sorghum yield and seeds selenium content were studied by the method of field experiment. The results showed that germination potential, germination rate and vigor index were significantly improved when the seeds were socked in 0.1~0.5 mg Se/L sodium selenite solution, which could promote the growth of young root and bud. Sodium selenite seed soaking had no significant effect on yield, it could improve seeds selenium content, but the effect was not obvious. Sodium selenite seed soaking could be used as a supplementary measure to enhance selenium content in sorghum seeds.