Abstract: The paper aims to elucidate the control effect of 10% triflumezopyrim suspension on rice planthoppers (including the white-backed planthopper, WBPH and brown planthopper, BPH), which are the main pests on rice, and the influence on spiders, the predator of planthoppers, and to provide references for the promotion and application of 10% triflumezopyrim suspension. Three treatments are set as 75 mL/hm2 (low dose), 150 mL/hm2 (medium dose) and 225 mL/hm2 (high dose), and 25% pymetrozine suspension 300 mL/hm2 and 25% thiamethoxam water dispersible granule 90 g/hm2 are used as positive control group, and water as blank control group. Each treatment repeated three times, and the drugs are sprayed during the outbreak of rice planthopper nymph. The results showed that compared with the positive control group, 10% triflumezopyrim suspension had the highest insecticidal activity. Field survey showed that, on the 14th day after drug spray, the control effect of low, middle and high dose of 10% triflumezopyrim suspension was 95.16% , 96.78% and 100.00% on WBPH respectively, and 90.29%, 96.07% and 93.81% on BPH respectively. High dose treatment had certain influence on spiders, 21-35 days after drug spray, there was a little decline of spider numbers. Middle and low dose treatment had slightly influence on spiders in field. After 35 days of drug spray, the total number of spiders decreased a little. The safety of triflumezopyrim on spider was higher than that of the positive control group. 10% triflumezopyrim suspension not only show good control effect on rice planthoppers, but also has relatively long lasting time, and less influence on the predator of planthopper. So, it could be prompted and applied in rice production.