Abstract: The paper aims to understand the variation characteristics of extreme temperature in Chamdo, and provide references for local agricultural and animal husbandry production and disaster prevention and mitigation. Based on daily temperature (maximum, minimum and average) data of Chamdo station, we analyzed the variation characteristics of extreme temperature indexes in Chamdo from 1961 to 2015. The results showed that: the extreme maximum temperature and extreme minimum temperature generally increased, the tendency rate was 0.25℃/10 a and 0.46℃/10 a, respectively; frost days, cold days and cold nights declined; warm days and warm nights and summer days increased; most indexes had the mutation passing significance test, the mutation point of cold indexes (including TNn, FD, TN10, TX10) happened in 1990s and that of warm indexes (including TXx, SU25, TN90, TX90) happened in 2004-2006 and only one mutation was observed; all extreme temperature indexes had the oscillation period with 3-5 years, and also had other oscillation periods with different distribution periods; the extreme temperature indexes had good response to climate warming, especially the cold indexes; due to the unique geographical location of Chamdo, the variation characteristics of extreme temperature in Chamdo were unique. Variation characteristics of extreme temperature will have a huge impact on agricultural and animal husbandry production in Chamdo.