Abstract: To clarify the effect of multi- trace elements on increasing yield of tomato, we conducted an experiment in greenhouse with the material of‘Beijing Boshou Huiteng 5’, and studied the influence of different fertilizer proportions on growth development, yield and quality of tomato by using comparison analysis method. The results showed that: under the same levels of NPK fertilization, increasing more medium and trace elements could improve the sugar content of tomato by 6.82%-18.18%, the yield by 1.18%-6.15%, the income by 1.23%- 6.59% ; compared with the control group (T1), the application of the medium application (T3) increased the plant height, stem diameter and promoted the flowering, fruit setting of tomato as well as the yield by 5759.40 kg/hm2 and increased income by 11462.70 yuan/hm2. Taking production, fertilizer and multi-trace elements into consideration, using the potassium sulphate compound fertilizer (15-15-15) 750 kg/hm2 and medium and trace element synergistic package 4.5 kg/hm2 as base fertilizer, the potassium sulphate compound fertilizer (15-5-25) 1350 kg/hm2 and medium and trace element synergistic package 8.1 kg/hm2 as top dressing (6 times application of fertilizer and synergistic package) could improve the yield and quality of tomato, promote flowering and fruit set, early market, and the fertilization formula can be used as the best for tomato production.