Application of Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry in Pesticide Residue Detection

doi:10.11923/j.issn.2095-4050.cjas18040026

Abstract

Abstract: According to the basic influence factors of multi-pesticide residues detection by Ultra High Performance Liquid Chromatography (UPLC)- tandem Mass Spectrometry (MS/MS), the key points of literatures in recent years about pesticide residues detection by UPLC-MS/MS were summarized, including extraction technology, purification process, selection of chromatographic column, type of mass spectrometry and ion source model for samples of different matrix. It was considered that the pretreatment of biological samples and removal of matrix effects had important effects on the accuracy of the results, because biological samples were usually complex and the endogenous substances would interfere with the determination of the target substance. Then, the main factors that need to be considered in establishment of UPLC-MS/MS were proposed.

CLC Number:

S481

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