Abstract: Using "Zhengdan 958" as a test material, 8 kinds of chemicals were selected, and 10 treatments were set up to conduct field trials. The results showed that seed coating had good control effect on corn underground pests and Laodelphax striatellus. 31% oligosaccharide ? Thiofenil seed coating + 14% chlorantran ? high chlorofluorocarbon sputum spraying, corn mites control effect is 90.35%～93.96%, locust control effect is 91.82%～92.72%, both are significantly higher than Spray separately. Spraying 18.7% of acyclovir, azoxystrobin, 75% of pyrazole, azoxystrobin, and tebuconazole have good control effects on corn leaf spot and southern rust. In the tasseling period, the control effect on small spot disease, brown spot disease and southern rust was 18.3%, and the azoxystrobin was 83.36%, 76.51%, and 78.93%, respectively; 75% of the ethiazole and azoxystrobin were 79.25. %, 75.76%, 83.81%; 75% sputum and tebuconazole were 76.32%, 82.83%, and 74.51%, respectively. Different drug treatments significantly increased yield compared to