Abstract: In order to compare the application efficiency of pure S-based compound fertilizer (N:P:K=20:10:21) and common compound fertilizer (N:P:K=15:15:15), the growth characteristics, fruit quality, yield and economic benefit of‘Red Fuji’apple of 13 years old were studied in the article. The results showed that th e leaf number and area of new shoots were the highest under pure S- based compound fertilizer of Stanley treatment, the leaf number was 23.5, and the leaf area was 62.5 cm2. Compared with the control, the ratio of sugar and acid decreased by 3.7% under the common compound fertilizer treatment, and increased by 13.1% under the pure S-based compound fertilizer treatment. The yield of apple was 56160 kg/hm2 under pure Sbased compound fertilizer treatment, which was 13110 kg/hm2 more than that in control and 4620 kg/hm2 more than that under compound fertilizer treatment, yield increasing rate was 30.4% and 8.9%, respectively. The shoot growth was promoted, leaf area, fruit soluble solid content and sugar acid ratio was increased, fruit quality and yield was improved significantly under pure S-based compound fertilizer treatment.