Abstract: The study aims to explore the antifungal effects of eight agents on phytophthora infestan, the pathogen fungus of tomato late blight. Drug-containing medium was used to determine the indoor inhibitory role of 8 experimental antifungal agents on P. infestan. Experimental results showed that the 8 agents all had inhibition effects on P. infestan and the antifungal rates increased with the concentration. 72% cymoxanil mancozeb WP, 50% flumorph mancozeb WP, 60% pyraclostrobin metiram WG and 20% athomin EW had the best antifungal effect on P. infestan, and their antifungal rates were 100% after 7 days of application.