Abstract: This article reviewed the experience and development trends of food safety management in developed countries from the perspective of the supervision system of agro-product safety. Combined with the problems in establishment and implementation of agro-product quality and safety system in China, the authors proposed suggestions on improving the supervision system of agro- product quality and safety. Firstly, to establish the supervision system covering the whole process and factors of agricultural production through toplevel design; secondly, to develop a dynamic supervision model based on pre- real- time monitoring and information sharing concentrating on the source control; thirdly, to strengthen the resource integration and condition guarantee while building stable channels for funds and subsidies; finally, to build a multifactor and coordinated supervision mechanism with the involvement of government, society, enterprises and consumers.