Abstract: To study the high-quality tobacco growing areas in Sanmenxia, based on data from the climatic stations located in the national tobacco areas of Sanmenxia, we analyzed the similarity of different tobacco areas both at home and abroad, and classified the tobacco areas in Sanmenxia via multivariate clustering analysis. The results showed that, the data from climatic stations could faithfully represent the Climatic Feasibility Index (CFI) of each tobacco area because of the drastic difference of sea levels within Sanmenxia area. The clustering analysis could tell that the climate of Lushi and Lingbao tobacco areas had the most similarity with the tobacco area in Zimbabwe, high level similarity with the one in Brazil, and medium level similarity with the one in the US, indicating that Lushi and Lingbao had excellent tobacco-growing climatic conditions. In the trend of continuing decrement of the tobacco growing scale, Lushi and Lingbao tobacco areas should be considered with priority in Sanmenxia.