Abstract: The climate factors, soil nutrient status and the quality characteristics of flue-cured tobacco leaves in Sichuan Province Dazhou were analyzed. results showed that,Dazhou flue-cured tobacco growing areas was humid subtropical monsoon climate, had the characteristics of mild climate, moderate rainfall, adequate light, heat is rich, air humidity. It showed that the ecological conditions of Dazhou flue-cured tobacco growing areas were suitable for the growth of tobacco. The soil in Sichuan Province Daxian was suitable, organic matter content in the most suitable medium, the CEC of soil was suitable, most of nutrition element content in soil were rich or appropriate, natural selenium in soil was rich, phosphorus and potassium were insufficient, zinc was lack, boron was extreme lack. The physical characteristics and chemical composition were suitable, the style characteristic of flue-cured tobacco was obvious, sensory quality was better.