Abstract: In order to screen out the safe and efficient fungicides for wheat scab control, a field experiment of 4 kinds of new fungicides on wheat scab was set up, including 20% triadimefon EC, 70% tebuconazole WG, 50% carbendazim WP, 25% beta suspension. At the same management level, a large area comparative demonstration was conducted in compare with the control group treated with water. Results showed that the yield of water treatment was 7976.01 kg/hm2. Among the 4 treatments, the highest yield was 8455.77 kg/hm2 with 25% beta suspension 1500 mL/hm2, increased by 479.76 kg compared with the control with an increasing rate of 6%. The second-highest yield was 8155.92 kg/hm2 with 50% carbendazim WP 1500 mL/hm2, increased by179.91 kg compared with the control with an increasing rate of 2.3%. 20% Triadimefon EC 750 mL/hm2 and 70% tebuconazole WG 150 mL/hm2 had no significant difference from the control group. It was concluded that 25% beta suspension 1500 mL/hm2 had the best control effect, in the spraying heading to flowering stage, it could effectively prevent the occurrence of scab for a higher yield.