Abstract: For the ecological environment with frequent drought, cold damage, cold in the late spring and dry hot wind during the wheat growing season in the hilly areas of Shandong Province, the new wheat variety ‘Yannong 173’, which has the advantages of water-and-dry land adaptation, multi-resistance and high yield, was bred by the Wheat Research Institute of Yantai Academy of Agricultural Sciences, Shandong Province, by cross- fertilized with the female parent‘Jimai 22’and the male parent‘Yan 2415’using the systematic methods of water-and-drought integrated planting, parallel superiority selection, stress-resistant ecological selection and water-drought combined assessment. The average yield of‘Yannong 173’in Shandong Regional Wheat Trials was 8982.2 kg/hm2 from 2012 to 2014, increased by 6.17% compared with that of the control ‘Jimai 22’. In the Shandong Production Test, the average yield of‘Yannong 173’was 8719.4 kg/hm2 during 2014-2015, increased by 4.70% compared with that of‘Jimai 22’. In February 2016,‘Yannong 173’was approved by the Shandong Provincial Crop Variety Approval Committee, and the certification number was 2016005. The variety has the characteristics of high and stable yield, drought resistance, water saving, cold resistance, late spring cold resistance, dry heat resistance, good mature yellowing, excellent agronomic traits and good commodity quality, and is suitable for planting at medium-and-high fertilizer and water farmland, as well as at dry farmland in Shandong, Shanxi and Hebei Province.