Abstract: Potassium was one of the elements essential for the growth and development of Flue-cured Tobacco, potassium content was an important indicator of quality of Flue-cured Tobacco, low potassium content of Flue-cured Tobacco had severely restricted the development of tobacco production. Therefore, it was of great practical significance to improve the potassium content of Flue-cured Tobacco to improve the quality of Flue-cured Tobacco in China.The authors reviewed the effect of potassium on physiological function and quality of Flue-cured Tobacco, effect of biological potassium fertilizer on development, potassium content, quality of Flue-cured Tobacco and conditions for effective application of biological potassium fertilizer. The effects of biological potassium fertilizer on the growth, yield and quality of Flue-cured Tobacco were summarized, On the basis of the above discussion, the techniques for increasing the potassium content of Flue-cured Tobacco were proposed, it was believed that biological potassium fertilizer was one of the effective ways to improve the quality of Flue-cured Tobacco in China,The authors made an outlook on the future research of biological potassium fertilizer.