To analyze the effects of temperature change in different growth stages on winter wheat. Based on the average temperature data of Yantai from 1971 to 2015, we studied the inter-annual changes, the decadal change rates and mutations by using the linear trend rate and Mann-Kendall test. The results showed that: the average temperature in the whole growth period, the vegetative period, the vegetative and reproductive growth period, the reproductive growth period increased at the rate of 0.15℃/10 a (P<0.01), 0.12℃/10 a (P<0.05), 0.21℃/10 a (P<0.01) and 0.28℃/10 a (P<0.01), respectively; the coefficient of variation and the mutations in the vegetative period, the vegetative and reproductive growth period, the reproductive growth period and the whole growth period was 17.27%, 11.80%, 3.94%, 8.05%, respectively, appeared in 1987, 1991, 1981 and 1982, respectively. The increase of temperature eventually makes it difficult to complete the vernalization phase and shortens the bud differentiation period, besides, the reproductive growth period may experience extreme weather such as hot-arid wind in early summer, which may cause a drop in wheat yield. Under the background of global warming, we should conform to climate change, reasonably match winter wheat varieties and take corresponding management measures to promote the sustainable development of high yield and high quality of agriculture in Yantai.